Description
A mixture of ganglioside GD3 with variable fatty acyl chains; induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential at 200 µM; expression in GD3-negative SK-MEL-28-N1 malignant melanoma cells increases both cell proliferation and invasion in vitro; ganglioside GD3-deficient adult mice exhibit progressive loss of the NSC pool and impaired neurogenesis